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Netrin-1 overexpression in kidney proximal tubular epithelium ameliorates cisplatin nephrotoxicity

Netrin-1, a multifunctional laminin-related protein is widely expressed in various tissues, including kidney. The pathophysiological roles of netrin-1 in toxic acute kidney injury are unknown. To determine the role of netrin-1 in cisplatin-induced nephrotoxicity, we used netrin-1 transgenic mice tha...

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Detalhes bibliográficos
Main Authors: Rajasundari, Amala, Pays, Laurent, Mehlen, Patrick, Ramesh, Ganesan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411324/
https://ncbi.nlm.nih.gov/pubmed/21876536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2011.126
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