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Exogenous spermidine ameliorates tubular necrosis during cisplatin nephrotoxicity

The hallmark of cisplatin-induced acute kidney injury is the necrotic cell death in the kidney proximal tubules. However, an effective approach to limit cisplatin nephrotoxicity remains unknown. Spermidine is a polyamine that protects against oxidative stress and necrosis in aged yeasts, and the pre...

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Опубликовано в: :Anat Cell Biol
Главные авторы: Yoon, Sang Pil, Kim, Jinu
Формат: Artigo
Язык:Inglês
Опубликовано: Korean Association of Anatomists 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172597/
https://ncbi.nlm.nih.gov/pubmed/30310711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5115/acb.2018.51.3.189
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