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Cisplatin induces primary necrosis through poly(ADP-ribose) polymerase 1 activation in kidney proximal tubular cells

Treatment with cisplatin for cancer therapy has a major side effect such as nephrotoxicity; however, the role of poly (ADP-ribose) polymerase 1 (PARP1) in necrosis in response to cisplatin nephrotoxicity remains to be defined. Here we report that cisplatin induces primary necrosis through PARP1 acti...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Anat Cell Biol
Päätekijät: Park, Seulgee, Yoon, Sang Pil, Kim, Jinu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Korean Association of Anatomists 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371183/
https://ncbi.nlm.nih.gov/pubmed/25806124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5115/acb.2015.48.1.66
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