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Netrin-1 overexpression in kidney proximal tubular epithelium ameliorates cisplatin nephrotoxicity
Netrin-1, a multifunctional laminin-related protein is widely expressed in various tissues, including kidney. The pathophysiological roles of netrin-1 in toxic acute kidney injury are unknown. To determine the role of netrin-1 in cisplatin-induced nephrotoxicity, we used netrin-1 transgenic mice tha...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411324/ https://ncbi.nlm.nih.gov/pubmed/21876536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2011.126 |
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