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P-Glycoprotein Induction Ameliorates Colistin Induced Nephrotoxicity in Cultured Human Proximal Tubular Cells

The pathogenesis of colistin induced nephrotoxicity is poorly understood. Currently there are no effective therapeutic or prophylactic agents available. This study was aimed to determine the mechanism of colistin induced nephrotoxicity and to determine whether P-glycoprotein (P-gp) induction could p...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, Sun-hyo, Kim, Jin-sun, Ravichandran, Kameswaran, Gil, Hyo-Wook, Song, Ho-yeon, Hong, Sae-yong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545883/
https://ncbi.nlm.nih.gov/pubmed/26287374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136075
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