STALK CELL PHENOTYPE DEPENDS ON INTEGRATION OF NOTCH AND SMAD1/5 SIGNALING CASCADES

Gradients of VEGF induce single endothelial cells to become leading tip cells of emerging angiogenic sprouts. Tip cells then suppress tip cell features in adjacent stalk cells via Dll4/Notch mediated lateral inhibition. We report here that Smad1/Smad5 mediated BMP signaling synergizes with Notch sig...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Dev Cell
Hlavní autoři: Moya, Iván M., Umans, Lieve, Maas, Elke, Pereira, Paulo N. G., Beets, Karen, Francis, Annick, Sents, Ward, Robertson, Elizabeth J., Mummery, Christine L., Huylebroeck, Danny, Zwijsen, An
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544746/
https://ncbi.nlm.nih.gov/pubmed/22364862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.01.007
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky