Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions

Amyotrophic lateral sclerosis is a rapidly progressing neurodegenerative disease associated with protein misfolding and aggregation. Most cases are characterized by TDP-43 positive inclusions, while a minority of familial ALS cases are instead FUS and SOD1 positive respectively. Cells can generate i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Farrawell, Natalie E., Lambert-Smith, Isabella A., Warraich, Sadaf T., Blair, Ian P., Saunders, Darren N., Hatters, Danny M., Yerbury, Justin J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4544019/
https://ncbi.nlm.nih.gov/pubmed/26293199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13416
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia