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Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions
Amyotrophic lateral sclerosis is a rapidly progressing neurodegenerative disease associated with protein misfolding and aggregation. Most cases are characterized by TDP-43 positive inclusions, while a minority of familial ALS cases are instead FUS and SOD1 positive respectively. Cells can generate i...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4544019/ https://ncbi.nlm.nih.gov/pubmed/26293199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13416 |
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