Addition of exogenous SOD1 aggregates causes TDP-43 mislocalisation and aggregation

ALS is characterised by a focal onset of motor neuron loss, followed by contiguous outward spreading of pathology throughout the nervous system, resulting in paralysis and death generally within a few years after diagnosis. The aberrant release and uptake of toxic proteins including SOD1 and TDP-43...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Stress Chaperones
Main Authors: Zeineddine, Rafaa, Farrawell, Natalie E., Lambert-Smith, Isabella A., Yerbury, Justin J.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2017
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655364/
https://ncbi.nlm.nih.gov/pubmed/28560609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0804-y
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker