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Addition of exogenous SOD1 aggregates causes TDP-43 mislocalisation and aggregation
ALS is characterised by a focal onset of motor neuron loss, followed by contiguous outward spreading of pathology throughout the nervous system, resulting in paralysis and death generally within a few years after diagnosis. The aberrant release and uptake of toxic proteins including SOD1 and TDP-43...
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| 發表在: | Cell Stress Chaperones |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer Netherlands
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5655364/ https://ncbi.nlm.nih.gov/pubmed/28560609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0804-y |
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