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Tet1 is critical for neuronal activity-regulated gene expression and memory extinction
The ten-eleven translocation (Tet) family of methylcytosine dioxygenases catalyze oxidation of 5-methylcytosine (5mC) to 5-hydroxymethylacytosine (5hmC) and promote DNA demethylation. Despite the abundance of 5hmC and Tet proteins in the brain, little is known about the functions of the neuronal Tet...
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| Опубликовано в: : | Neuron |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4543319/ https://ncbi.nlm.nih.gov/pubmed/24050401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.08.003 |
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