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Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture

Topological domains are key architectural building blocks of chromosomes, but their functional importance and evolutionary dynamics are not well defined. We performed comparative high-throughput chromosome conformation capture (Hi-C) in four mammals and characterized the conservation and divergence...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Vietri Rudan, Matteo, Barrington, Christopher, Henderson, Stephen, Ernst, Christina, Odom, Duncan T., Tanay, Amos, Hadjur, Suzana
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542312/
https://ncbi.nlm.nih.gov/pubmed/25732821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.02.004
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