Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture

Topological domains are key architectural building blocks of chromosomes, but their functional importance and evolutionary dynamics are not well defined. We performed comparative high-throughput chromosome conformation capture (Hi-C) in four mammals and characterized the conservation and divergence...

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Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Vietri Rudan, Matteo, Barrington, Christopher, Henderson, Stephen, Ernst, Christina, Odom, Duncan T., Tanay, Amos, Hadjur, Suzana
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2015
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542312/
https://ncbi.nlm.nih.gov/pubmed/25732821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.02.004
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