Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture

Topological domains are key architectural building blocks of chromosomes, but their functional importance and evolutionary dynamics are not well defined. We performed comparative high-throughput chromosome conformation capture (Hi-C) in four mammals and characterized the conservation and divergence...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Vietri Rudan, Matteo, Barrington, Christopher, Henderson, Stephen, Ernst, Christina, Odom, Duncan T., Tanay, Amos, Hadjur, Suzana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542312/
https://ncbi.nlm.nih.gov/pubmed/25732821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.02.004
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