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Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders

BACKGROUND: Type II DNA topoisomerases (TOP2) regulate DNA topology by generating transient double stranded breaks during replication and transcription. Topoisomerase II beta (TOP2B) facilitates rapid gene expression and functions at the later stages of development and differentiation. To gain new i...

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Bibliographische Detailangaben
Veröffentlicht in:Genome Biol
Hauptverfasser: Uusküla-Reimand, Liis, Hou, Huayun, Samavarchi-Tehrani, Payman, Rudan, Matteo Vietri, Liang, Minggao, Medina-Rivera, Alejandra, Mohammed, Hisham, Schmidt, Dominic, Schwalie, Petra, Young, Edwin J., Reimand, Jüri, Hadjur, Suzana, Gingras, Anne-Claude, Wilson, Michael D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006368/
https://ncbi.nlm.nih.gov/pubmed/27582050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1043-8
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