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Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders

BACKGROUND: Type II DNA topoisomerases (TOP2) regulate DNA topology by generating transient double stranded breaks during replication and transcription. Topoisomerase II beta (TOP2B) facilitates rapid gene expression and functions at the later stages of development and differentiation. To gain new i...

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Dades bibliogràfiques
Publicat a:Genome Biol
Autors principals: Uusküla-Reimand, Liis, Hou, Huayun, Samavarchi-Tehrani, Payman, Rudan, Matteo Vietri, Liang, Minggao, Medina-Rivera, Alejandra, Mohammed, Hisham, Schmidt, Dominic, Schwalie, Petra, Young, Edwin J., Reimand, Jüri, Hadjur, Suzana, Gingras, Anne-Claude, Wilson, Michael D.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006368/
https://ncbi.nlm.nih.gov/pubmed/27582050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1043-8
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