Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders

BACKGROUND: Type II DNA topoisomerases (TOP2) regulate DNA topology by generating transient double stranded breaks during replication and transcription. Topoisomerase II beta (TOP2B) facilitates rapid gene expression and functions at the later stages of development and differentiation. To gain new i...

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Vydáno v:Genome Biol
Hlavní autoři: Uusküla-Reimand, Liis, Hou, Huayun, Samavarchi-Tehrani, Payman, Rudan, Matteo Vietri, Liang, Minggao, Medina-Rivera, Alejandra, Mohammed, Hisham, Schmidt, Dominic, Schwalie, Petra, Young, Edwin J., Reimand, Jüri, Hadjur, Suzana, Gingras, Anne-Claude, Wilson, Michael D.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006368/
https://ncbi.nlm.nih.gov/pubmed/27582050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1043-8
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