A CTCF-independent role for cohesin in tissue-specific transcription

The cohesin protein complex holds sister chromatids in dividing cells together and is essential for chromosome segregation. Recently, cohesin has been implicated in mediating transcriptional insulation, via its interactions with CTCF. Here, we show in different cell types that cohesin functionally b...

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Main Authors: Schmidt, Dominic, Schwalie, Petra C., Ross-Innes, Caryn S., Hurtado, Antoni, Brown, Gordon D., Carroll, Jason S., Flicek, Paul, Odom, Duncan T.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860160/
https://ncbi.nlm.nih.gov/pubmed/20219941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.100479.109
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