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Transducin-like enhancer protein 1 mediates estrogen receptor binding and transcriptional activity in breast cancer cells
Estrogen receptor (ER) binds to distal enhancers within the genome and requires additional factors, such as the Forkhead protein FoxA1, for mediating chromatin interactions. We now show that the human Groucho protein, Transducin-like enhancer protein 1 (TLE1), positively assists some ER-chromatin in...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3286936/ https://ncbi.nlm.nih.gov/pubmed/21536917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018863108 |
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