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FOXA1 is a critical determinant of Estrogen Receptor function and endocrine response
Estrogen Receptor-α (ER) is the key feature in the majority of breast cancers and ER binding to the genome correlates with the Forkhead protein FOXA1 (HNF3α). We now show that FOXA1 is a critical determinant that can influence differential ER-chromatin interactions. We show that almost all ER-chroma...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3024537/ https://ncbi.nlm.nih.gov/pubmed/21151129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.730 |
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