Cooperative interaction between retinoic acid receptor-α and estrogen receptor in breast cancer

Retinoic acid receptor-α (RARα) is a known estrogen target gene in breast cancer cells. The consequence of RARα induction by estrogen was previously unknown. We now show that RARα is required for efficient estrogen receptor-α (ER)-mediated transcription and cell proliferation. RARα can interact with...

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Main Authors: Ross-Innes, Caryn S., Stark, Rory, Holmes, Kelly A., Schmidt, Dominic, Spyrou, Christiana, Russell, Roslin, Massie, Charlie E., Vowler, Sarah L., Eldridge, Matthew, Carroll, Jason S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807352/
https://ncbi.nlm.nih.gov/pubmed/20080953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.552910
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