Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells

BACKGROUND: The forkhead transcription factor FOXM1 is a key regulator of the cell cycle. It is frequently over-expressed in cancer and is emerging as an important therapeutic target. In breast cancer FOXM1 expression is linked with estrogen receptor (ERα) activity and resistance to endocrine therap...

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Hlavní autoři: Sanders, Deborah A, Ross-Innes, Caryn S, Beraldi, Dario, Carroll, Jason S, Balasubramanian, Shankar
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663086/
https://ncbi.nlm.nih.gov/pubmed/23347430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-1-r6
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