Waves of Retrotransposon Expansion Remodel Genome Organization and CTCF Binding in Multiple Mammalian Lineages

CTCF-binding locations represent regulatory sequences that are highly constrained over the course of evolution. To gain insight into how these DNA elements are conserved and spread through the genome, we defined the full spectrum of CTCF-binding sites, including a 33/34-mer motif, and identified ove...

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Main Authors: Schmidt, Dominic, Schwalie, Petra C., Wilson, Michael D., Ballester, Benoit, Gonçalves, Ângela, Kutter, Claudia, Brown, Gordon D., Marshall, Aileen, Flicek, Paul, Odom, Duncan T.
Format: Artigo
Language:Inglês
Published: Cell Press 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368268/
https://ncbi.nlm.nih.gov/pubmed/22244452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.11.058
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