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Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules

The cohesin protein complex contributes to transcriptional regulation in a CTCF-independent manner by colocalizing with master regulators at tissue-specific loci. The regulation of transcription involves the concerted action of multiple transcription factors (TFs) and cohesin's role in this con...

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Detalhes bibliográficos
Main Authors: Faure, Andre J., Schmidt, Dominic, Watt, Stephen, Schwalie, Petra C., Wilson, Michael D., Xu, Huiling, Ramsay, Robert G., Odom, Duncan T., Flicek, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483546/
https://ncbi.nlm.nih.gov/pubmed/22780989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.136507.111
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