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Cu(II) Promotes Amyloid Pore Formation

The aggregation of α-synuclein is associated with dopamine neuron death in Parkinson's disease. There is controversy in the field over the question of which species of the aggregates, fibrils or protofibrils, are toxic. Moreover, compelling evidence suggested the exposure to heavy metals to be...

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Bibliographische Detailangaben
Veröffentlicht in:Biochem Biophys Res Commun
Hauptverfasser: Zhang, Hangyu, Rochet, Jean-Christophe, Stanciu, Lia A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542091/
https://ncbi.nlm.nih.gov/pubmed/26129772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.06.156
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