A trishistidine pseudopeptide with ability to remove both Cu(i) and Cu(ii) from the amyloid-β peptide and to stop the associated ROS formation

The pseudopeptide L, derived from a nitrilotriacetic acid scaffold and functionalized with three histidine moieties, is reminiscent of the amino acid side chains encountered in the Alzheimer’s peptide (Aβ). Its synthesis and coordination properties for Cu(i) and Cu(ii) are described. L efficiently c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Conte-Daban, A., Boff, B., Candido Matias, A., Aparicio, C. N. Montes, Gateau, C., Lebrun, C., Cerchiaro, G., Kieffer, I., Sayen, S., Guillon, E., Delangle, P., Hureau, C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714062/
https://ncbi.nlm.nih.gov/pubmed/28846165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201703429
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados