A trishistidine pseudopeptide with ability to remove both Cu(i) and Cu(ii) from the amyloid-β peptide and to stop the associated ROS formation

The pseudopeptide L, derived from a nitrilotriacetic acid scaffold and functionalized with three histidine moieties, is reminiscent of the amino acid side chains encountered in the Alzheimer’s peptide (Aβ). Its synthesis and coordination properties for Cu(i) and Cu(ii) are described. L efficiently c...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Chemistry
Asıl Yazarlar: Conte-Daban, A., Boff, B., Candido Matias, A., Aparicio, C. N. Montes, Gateau, C., Lebrun, C., Cerchiaro, G., Kieffer, I., Sayen, S., Guillon, E., Delangle, P., Hureau, C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714062/
https://ncbi.nlm.nih.gov/pubmed/28846165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201703429
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