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Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases
The minichromosome maintenance (MCM) 2-7 helicase complex functions to initiate and elongate replication forks. Cell cycle checkpoint signaling pathways regulate DNA replication to maintain genomic stability. We describe four lines of evidence that ATM/ATR-dependent (ataxia-telangiectasia-mutated/AT...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC454167/ https://ncbi.nlm.nih.gov/pubmed/15210935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403410101 |
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