Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress
The BRCA1 gene encodes a tumor suppressor that is mutated in 50% of familial breast cancers. The BRCA1 protein has been implicated in the DNA damage response, as DNA damage induces the phosphorylation of BRCA1 and causes its recruitment into nuclear foci that contain DNA repair proteins. The ataxia-...
Sábháilte in:
| Foilsithe in: | Genes Dev |
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| Príomhchruthaitheoirí: | , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
Cold Spring Harbor Laboratory Press
2000
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317107/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11114888/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.851000 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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