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Artemis Is a Phosphorylation Target of ATM and ATR and Is Involved in the G(2)/M DNA Damage Checkpoint Response
Mutations in Artemis in both humans and mice result in severe combined immunodeficiency due to a defect in V(D)J recombination. In addition, Artemis mutants are radiosensitive and chromosomally unstable, which has been attributed to a defect in nonhomologous end joining (NHEJ). We show here, however...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC517881/ https://ncbi.nlm.nih.gov/pubmed/15456891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.20.9207-9220.2004 |
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