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657del5 mutation of the NBS1 gene in myelodysplastic syndrome

Myelodysplastic syndromes (MDS) are clonal hematologic stem cell disorders with an as yet unknown molecular pathology. Genetic instability has been proposed as a cause of MDS. Mutations in the NBS1 gene, whose product nibrin (p95) is involved in DNA damage repair and cell-cycle control, mig...

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Autori principali: Bunjevacki Vera, Maksimovic Nela, Damnjanovic Tatjana, Cvjeticanin Suzana, Novakovic Ivana, Lukovic Ljiljana, Ristanovic Momcilo, Bogdanovic Andrija, Jekic Biljana
Natura: Artigo
Lingua:Inglês
Pubblicazione: University of Belgrade, University of Novi Sad 2014-01-01
Serie:Archives of Biological Sciences
Soggetti:
MDS
nibrin
NBS1 mutations
657del5
Accesso online:http://www.doiserbia.nb.rs/img/doi/0354-4664/2014/0354-46641403055B.pdf
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