Artemis Is a Phosphorylation Target of ATM and ATR and Is Involved in the G(2)/M DNA Damage Checkpoint Response

Mutations in Artemis in both humans and mice result in severe combined immunodeficiency due to a defect in V(D)J recombination. In addition, Artemis mutants are radiosensitive and chromosomally unstable, which has been attributed to a defect in nonhomologous end joining (NHEJ). We show here, however...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Zhang, Xiaoshan, Succi, Janice, Feng, Zhaohui, Prithivirajsingh, Sheela, Story, Michael D., Legerski, Randy J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2004
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517881/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15456891/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.20.9207-9220.2004
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