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A Role for Peptides in Overcoming Endosomal Entrapment in siRNA Delivery – A Focus on Melittin

siRNA has the possibility to revolutionize medicine by enabling highly specific and efficient silencing of proteins involved in disease pathogenesis. Despite nearly 20 years of research dedicated to translating siRNA from a research tool into a clinically relevant therapeutic, minimal success has be...

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Bibliografische gegevens
Gepubliceerd in:Biotechnol Adv
Hoofdauteurs: Hou, Kirk K., Pan, Hua, Schlesinger, Paul H., Wickline, Samuel A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540690/
https://ncbi.nlm.nih.gov/pubmed/26025036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biotechadv.2015.05.005
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