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A Role for Peptides in Overcoming Endosomal Entrapment in siRNA Delivery – A Focus on Melittin

siRNA has the possibility to revolutionize medicine by enabling highly specific and efficient silencing of proteins involved in disease pathogenesis. Despite nearly 20 years of research dedicated to translating siRNA from a research tool into a clinically relevant therapeutic, minimal success has be...

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Detalhes bibliográficos
Publicado no:Biotechnol Adv
Main Authors: Hou, Kirk K., Pan, Hua, Schlesinger, Paul H., Wickline, Samuel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540690/
https://ncbi.nlm.nih.gov/pubmed/26025036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biotechadv.2015.05.005
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