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Mechanisms of Nanoparticle Mediated siRNA Transfection by Melittin-Derived Peptides
Traditional peptide-mediated siRNA transfection via peptide transduction domains exhibits limited cytoplasmic delivery of siRNA due to endosomal entrapment. This work overcomes these limitations with the use of membrane-destabilizing peptides derived from melittin for the knockdown of NFkB signaling...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4013830/ https://ncbi.nlm.nih.gov/pubmed/24053333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn403311c |
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