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Melittin Derived Peptides for Nanoparticle Based siRNA Transfection

Traditional transfection agents including cationic lipids and polymers have high efficiency but cause cytotoxicity. While cell penetrating peptide based transfection agents exhibit improved cytotoxicity profiles, they do not have the efficiency of existing lipidic agents due to endosomal trapping. A...

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Bibliografiske detaljer
Main Authors: Hou, Kirk K., Pan, Hua, Lanza, Gregory M., Wickline, Samuel A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578292/
https://ncbi.nlm.nih.gov/pubmed/23380356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.01.037
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