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Calpain-2 inhibitor therapy reduces murine colitis and colitis associated cancer
BACKGROUND: An important role has emerged for calpain enzymes in regulating inflammation with one isoform, calpain-2, particularly important for macrophage activation. The goal of this study was to determine the therapeutic potential of a synthetic calpain-2 inhibitor, zLLY-CH2F, for colitis and inf...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Inflamm Bowel Dis |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4540674/ https://ncbi.nlm.nih.gov/pubmed/26076056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000471 |
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