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Cationic Lipsomes Promote in Vivo Transfection, Innate Immunity Activation and Antigen-Specific CD8+ T-Cell Activation Following Vaccination with Piggybac DNA Plasmids

INTRODUCTION: DNA vaccination with plasmid has conventionally involved vectors designed for transient expression of antigen in injected tissues. Next generation plasmids are being developed for site-directed integration of transgenes into safe sites in host genomes and may provide an innovative appr...

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Detalhes bibliográficos
Publicado no:Hawaii J Med Public Health
Main Authors: Hara, Jared, Bertino, Pietro, Hoffmann, FuKun W, Rose, Aaron H, Moisyadi, Stefan, Hoffmann, Peter R
Formato: Artigo
Idioma:Inglês
Publicado em: University Clinical, Education & Research Associate (UCERA) 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582363/
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