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Calpain-2 inhibitor therapy reduces murine colitis and colitis associated cancer
BACKGROUND: An important role has emerged for calpain enzymes in regulating inflammation with one isoform, calpain-2, particularly important for macrophage activation. The goal of this study was to determine the therapeutic potential of a synthetic calpain-2 inhibitor, zLLY-CH2F, for colitis and inf...
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| Publicat a: | Inflamm Bowel Dis |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4540674/ https://ncbi.nlm.nih.gov/pubmed/26076056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000471 |
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