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Calpain‐2 inhibitor treatment preferentially reduces tumor progression for human colon cancer cells expressing highest levels of this enzyme

Calpain‐2 levels are higher in colorectal tumors resistant to chemotherapy and previous work showed calpain‐2 inhibitor therapy reduced inflammation‐driven colorectal cancer, but direct effects of the inhibitor on colon cancer cells themselves were not demonstrated. In the present study, five human...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Marciel, Michael P., Rose, Aaron H., Martinez, Verena, Horio, David T., Hashimoto, Ann S., Hoffmann, FuKun W., Bertino, Pietro, Hoffmann, Peter R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773958/
https://ncbi.nlm.nih.gov/pubmed/29210197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1260
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