Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis

Doublecortin-like kinase 1 (Dclk1), a microtubule-associated kinase, marks the fifth lineage of intestinal epithelial cells called tuft cells that function as tumor stem cells in Apc mutant models of colon cancer. In order to determine the role of Dclk1 in dextran sulfate sodium (DSS) induced coloni...

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Publicado en:PLoS One
Autores principales: Qu, Dongfeng, Weygant, Nathaniel, May, Randal, Chandrakesan, Parthasarathy, Madhoun, Mohammad, Ali, Naushad, Sureban, Sripathi M., An, Guangyu, Schlosser, Michael J., Houchen, Courtney W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540568/
https://ncbi.nlm.nih.gov/pubmed/26285154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134212
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