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Inhibition of Notch signaling reduces the number of surviving Dclk1(+) reserve crypt epithelial stem cells following radiation injury
We have previously reported that doublecortin-like kinase 1 (Dclk1) is a putative intestinal stem cell (ISC) marker. In this report, we evaluated the use of Dclk1 as a marker of surviving ISCs in response to treatment with high-dose total body irradiation (TBI). Both apoptotic and mitotic Dclk1(+) c...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3949020/ https://ncbi.nlm.nih.gov/pubmed/24368703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00088.2013 |
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