Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism

Tumor stem cell marker Doublecortin-like kinase1 (DCLK1) is upregulated in several solid tumors. The role of DCLK1 in hepatocellular carcinoma (HCC) is unclear. We immunostained tissues from human livers with HCC, cirrhosis controls (CC), and non-cirrhosis controls (NCC) for DCLK1. Western blot and...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sureban, Sripathi M., Madhoun, Mohammad F., May, Randal, Qu, Dongfeng, Ali, Naushad, Fazili, Javid, Weygant, Nathaniel, Chandrakesan, Parthasarathy, Ding, Kai, Lightfoot, Stanley A., Houchen, Courtney W.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741924/
https://ncbi.nlm.nih.gov/pubmed/26468984
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