Dclk1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition

Doublecortin-like kinase 1 (Dclk1) is overexpressed in many cancers including colorectal cancer (CRC) and it specifically marks intestinal tumor stem cells. However, the role of Dclk1 in intestinal tumorigenesis in Apc mutant conditions is still poorly understood. We demonstrate that Dclk1 expressio...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Chandrakesan, Parthasarathy, Weygant, Nathaniel, May, Randal, Qu, Dongfeng, Chinthalapally, Harisha R., Sureban, Sripathi M., Ali, Naushad, Lightfoot, Stan A., Umar, Shahid, Houchen, Courtney W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253433/
https://ncbi.nlm.nih.gov/pubmed/25211188
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