Fluvastatin Interferes with Hepatitis C Virus Replication via Microtubule Bundling and a Doublecortin-like Kinase-Mediated Mechanism

Hepatitis C virus (HCV)-induced alterations in lipid metabolism and cellular protein expression contribute to viral pathogenesis. The mechanism of pleiotropic actions of cholesterol-lowering drugs, statins, against HCV and multiple cancers are not well understood. We investigated effects of fluvasta...

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Detalhes bibliográficos
Main Authors: Ali, Naushad, Allam, Heba, Bader, Ted, May, Randal, Basalingappa, Kanthesh M., Berry, William L., Chandrakesan, Parthasarathy, Qu, Dongfeng, Weygant, Nathaniel, Bronze, Michael S., Umar, Shahid, Janknecht, Ralf, Sureban, Sripathi M., Huycke, Mark, Houchen, Courtney W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833963/
https://ncbi.nlm.nih.gov/pubmed/24260365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080304
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