HTLV-1 Tax Stimulates Ubiquitin E3 Ligase, Ring Finger Protein 8, to Assemble Lysine 63-Linked Polyubiquitin Chains for TAK1 and IKK Activation

Human T lymphotropic virus type 1 (HTLV-1) trans-activator/oncoprotein, Tax, impacts a multitude of cellular processes, including I-κB kinase (IKK)/NF-κB signaling, DNA damage repair, and mitosis. These activities of Tax have been implicated in the development of adult T-cell leukemia (ATL) in HTLV-...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Ho, Yik-Khuan, Zhi, Huijun, Bowlin, Tara, Dorjbal, Batsukh, Philip, Subha, Zahoor, Muhammad Atif, Shih, Hsiu-Ming, Semmes, Oliver John, Schaefer, Brian, Glover, J. N. Mark, Giam, Chou-Zen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540474/
https://ncbi.nlm.nih.gov/pubmed/26285145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005102
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados