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Regulation of Human T-Lymphotropic Virus Type I Latency and Reactivation by HBZ and Rex
Human T lymphotropic virus type I (HTLV-I) infection is largely latent in infected persons. How HTLV-1 establishes latency and reactivates is unclear. Here we show that most HTLV-1-infected HeLa cells become senescent. By contrast, when NF-κB activity is blocked, senescence is averted, and infected...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3974842/ https://ncbi.nlm.nih.gov/pubmed/24699669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004040 |
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