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Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural Product–Drug Interaction

Women at high risk of developing breast cancer are prescribed selective estrogen response modulators, including raloxifene, as chemoprevention. Patients often seek complementary and alternative treatment modalities, including herbal products, to supplement prescribed medications. Milk thistle prepar...

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Dades bibliogràfiques
Publicat a:Drug Metab Dispos
Autors principals: Gufford, Brandon T., Chen, Gang, Vergara, Ana G., Lazarus, Philip, Oberlies, Nicholas H., Paine, Mary F.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538855/
https://ncbi.nlm.nih.gov/pubmed/26070840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.065086
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