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Chemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan Glucuronides

Plant-based therapeutics, including herbal products, continue to represent a growing facet of the contemporary health care market. Mechanistic descriptions of the pharmacokinetics and pharmacodynamics of constituents composing these products remain nascent, particularly for metabolites produced foll...

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Détails bibliographiques
Publié dans:Drug Metab Dispos
Auteurs principaux: Gufford, Brandon T., Graf, Tyler N., Paguigan, Noemi D., Oberlies, Nicholas H., Paine, Mary F.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613946/
https://ncbi.nlm.nih.gov/pubmed/26316643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.066076
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