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Chemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan Glucuronides

Plant-based therapeutics, including herbal products, continue to represent a growing facet of the contemporary health care market. Mechanistic descriptions of the pharmacokinetics and pharmacodynamics of constituents composing these products remain nascent, particularly for metabolites produced foll...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Gufford, Brandon T., Graf, Tyler N., Paguigan, Noemi D., Oberlies, Nicholas H., Paine, Mary F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613946/
https://ncbi.nlm.nih.gov/pubmed/26316643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.066076
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