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Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining
Mammalian DNA ligase III (LigIII) functions in both nuclear and mitochondrial DNA metabolism. In the nucleus, LigIII has functional redundancy with DNA ligase I whereas LigIII is the only mitochondrial DNA ligase and is essential for the survival of cells dependent upon oxidative respiration. The un...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538836/ https://ncbi.nlm.nih.gov/pubmed/26130724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv652 |
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