Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining

Mammalian DNA ligase III (LigIII) functions in both nuclear and mitochondrial DNA metabolism. In the nucleus, LigIII has functional redundancy with DNA ligase I whereas LigIII is the only mitochondrial DNA ligase and is essential for the survival of cells dependent upon oxidative respiration. The un...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Kukshal, Vandna, Kim, In-Kwon, Hura, Gregory L., Tomkinson, Alan E., Tainer, John A., Ellenberger, Tom
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
Onderwerpen:
Nucleic Acid Enzymes
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538836/
https://ncbi.nlm.nih.gov/pubmed/26130724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv652
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