Rad51 and RecA juxtapose dsDNA ends ready for DNA ligase-catalyzed end-joining under recombinase-suppressive conditions

RecA-family recombinase-catalyzed ATP-dependent homologous joint formation is critical for homologous recombination, in which RecA or Rad51 binds first to single-stranded (ss)DNA and then interacts with double-stranded (ds)DNA. However, when RecA or Rad51 interacts with dsDNA before binding to ssDNA...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Konomura, Naoto, Arai, Naoto, Shinohara, Takeshi, Kobayashi, Jun, Iwasaki, Wakana, Ikawa, Shukuko, Kusano, Kohji, Shibata, Takehiko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224515/
https://ncbi.nlm.nih.gov/pubmed/27794044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw998
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